This pathogenic bacteria can prevent intestinal cancer

A bacteria called Salmonella can be used to prevent bowel cancer. A new study has shown that the bacteria can prevent cancer from attacking various cells in the patient's body.

Dec 3, 2024 - 11:10
This pathogenic bacteria can prevent intestinal cancer

Salmonella bacteria are commonly associated with food poisoning. In addition, one species of it also causes typhoid. In addition, its ability to prevent cancer has long been said, but after using it in therapy, it has been found that it is not that effective.

New research has indicated that Salmonella can be used to increase the level of 'T' cells. This is a type of white blood cell that protects the body from infection and disease and can destroy cancer cells.

In experiments on mice, the research team found that Salmonella usually prevents the attack of cancer cells by reducing the amino acid 'asparagine' in T cells.

The first author of the study and a researcher in the Department of Immunology at the University of Birmingham, Dr. Alastair Copeland said their research could “turn pathogenic bacteria like Salmonella into a cancer-fighting tool.”

“Why T cells, which are key to preventing cancer, are not effective enough in this treatment has long been a mystery,” he said.

“Now, we have identified the protein responsible for this. In addition, we have observed a genetic behavior that could fully demonstrate the potential of this therapy.”

Dr. Catherine Elliott, Director of Research at Cancer Research UK, which funded the study, said the research was “very exciting.” It even “shows the potential for more effective treatments for rectal and other cancers in the future.”

Salmonella can be present in the intestines of a number of animals, including chickens, cows, pigs. The bacteria can infect foods such as eggs, chicken and pork, as well as fruits and vegetables that have been in contact with livestock and manure.

Symptoms of Salmonella infection include diarrhea, abdominal pain, nausea, vomiting and fever. It usually forms a rash within 12 to 72 hours, which can last from four to seven days.

The study was published in the scientific journal Embo Molecular Medicine.